All articles by Aravind Kshatri

Global prevalence and distribution of cardiovascular diseases

Cardiovascular diseases (CVD) refers to a diverse range of conditions that affect the heart or blood vessels. Major types of CVDs’ include coronary heart disease, stroke and heart failure. CVDs’, still remain the major cause of death across all the regions of the world. In 2015, approximately 17.7 million people died across the globe due to CVDs’, which represents 31% of total global deaths (WHO, 2017). The established risk factors associated with CVDs’ are obesity, hypertension, diabetes, high cholesterol and smoking (Laslett et al., 2012). Read more »

The importance of benchmarking in biomarker discovery and validation

Benchmarking is a process of comparing and contrasting best existing methods to new emerging techniques and methodologies. Benchmarking in biomarker discovery is a method of setting a baseline for identification and classification of new protein and molecules profiling technologies. Biomarkers are the best aid in understanding the cause, progression, diagnosis, regression and outcome of treatment of a disease. A number of biomarkers are currently very popular in diagnosis and management of cardiovascular diseases, infections, immunological and genetic disorders as well as in cancer (Perera and Weinstein, 2000). Read more »

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