All articles by Yashika Kapoor

Novel drug development to curb malaria

Malaria is a mosquito borne blood disease, which remains a devastating global health problem. It is caused by the obligate intraerythrocytic protozoa belonging to genus Plasmodium. Due to the increased preventive measures including insecticide-treated bed nets and safety measures such as artemisinin based combination treatments (ACTs) the global malaria mortality rate has reduced by 30% (Bhattarai et al., 2007). Nevertheless, according to World Health Organization (WHO), it is estimated that approximately 200 million people around the world contract malaria resulting in 20% of deaths (WHO, 2016). Read more »

Allergic factors responsible for Asthma

Examination of allergic disease trends around the globe demands an in-depth study on possible risk factors that can lead to this group of diseases. These risk factors could help understand the varying prevalence rates of allergic disorders between countries that have been observed so far Read more »

Understanding effect size in CMA

In the previous article: Data entry formats in CMA, different data entry formats were shown. In the discussion surrounding meta-analysis, effect size holds the prime importance, when it comes to analysis. An effect size is the magnitude or size of an effect resulting from a clinical treatment. Thus, in Comprehensive Meta Analysis (CMA), it assumes the reference of “treatment effect”. As different studies generate different datasets of variable nature, hence the effect size for a given study cannot be constrained to one particular index or measure (“measures” will be used in the article). Read more »

Understanding the various data entry formats in CMA

The software interface was discussed in the previous articleIntroducing Comprehensive Meta analysis (CMA) software. To calculate the effect size, one needs to enter the data into specific data entry formats. This article will acquaint the user with the procedure of entering the data into the software. Read more »

Economic burden of rhinitis in India and USA

The prominence of allergic rhinitis continues to increase in India, with proven data from International study of asthma and allergies in childhood (ISSAC) studies. The Phase 1 conducted in 1998, reported a prevalence rate of 12.5% – 18.6% among children, which rose to 12.9%-23.6% in 2009 Phase-3 results. The patients are classifiable into two clinical groups on the basis of clinical profile they present, sneezers and runners and blockers. Read more »

Economic burden from Asthma in India and USA

Asthma presented substantial global burden, affecting 358.2 million people in 2015. A complex disease, it impairs the social, physical and psychological well-being of the affected. Furthermore, the asthmatic condition can be differentiated into controlled, partially controlled and uncontrolled. The differentiation finds its basis in the level of severity of clinical manifestations (Koshak, 2007). With respect to which the Global asthma report 2014 mentions the higher economic burden associated with the uncontrolled condition (The Global Asthma Network, 2014). Besides the level of manifestation, the level of development also finds an association with disease economic burden. In an attempt to bring out the economic burden borne by developing and developed regions, the discussion presents the case of USA and India. Read more »

Allergic asthma in developing and developed regions around the globe

Allergic asthma a well-known chronic disease, of heterogeneous nature, affects respiratory airways. It presents several phenotypes on the basis of the disease progress. These phenotypes form recognizable demographic and clinical clusters around the globe. These phenotypes include allergic asthma, non-allergic asthma, late-onset asthma, asthma with fixed airflow limitation and asthma with obesity. Amongst all the different phenotypes, allergic asthma is recognized most easily. It has become highly prevalent since the latter half of 20th century, in both developing and developed nations. Read more »

Therapeutic consideration and treatment of conjunctivitis, food and skin allergies

The allergic disorders present a wide array of manifestations in the humans, demanding unique therapeutic strategies. The previous article shed light on treatment strategies for lethal Anaphylaxis, allergic Rhinitis & Asthma. The ocular and skin allergies not only compromise the quality of life but also makes the patient self-conscious about appearance. Read more »

We are looking for candidates who have completed their master's degree or Ph.D. Click here to know more about our vacancies.