Importance of bioremediation and its future prospects

Bioremediation helps cleaning up polluted environments, including soils, groundwater and marine environments. Such systems can include bacteria, fungi, algae and plant species. They are capable of metabolizing, immobilizing or absorbing toxic compounds from their environment. However, a major advantage of these systems is that they are less harmful to the environment with minimum or no by-products. Moreover, conventional physical and chemical treatments are expensive and inefficient and cause more harm than good. Thus, by evaluating research undertaken in bioremediation so far. It is possible that more efficient and feasible bioreactors or products are designed. Furthermore, these systems could be capable of completely removing pollutants from the environment. Also, it leads to useful compounds as by-products.

Microbes are an efficient tool for bioremediation technology 

A common theme recurring in bioremediation studies is that majority of the species that have been discovered with remediating properties are capable of natural attenuation. However, researchers have adopted these species capable of naturally degrading contaminants (for example bioreactors). On the other hand, these organisms have also been selected naturally for bioremediation capabilities, when high concentrations of specific compounds have been introduced in their environment.

On the other hand, naturally selected species have found specific importance in oil and plastic bioremediation fields, evident from the vast body of research from Exxon Valdez and Deepwater Horizon oil spills. Furthermore, other equally important examples include mitigating heavy metal pollution (soil, aquatic and marine systems) as a result of industrialization, such as lead, chromium, mercury, and arsenic. Similarly, unique cases of industrial pollution that require bioremediation assistance include the radioactive metal, Uranium and also groups of recalcitrant by-products of pharmaceutical and textile manufacturing industries. In addition, studies of these naturally selected species can be advantageous in designing more efficient biological systems by virtue of isolating, modifying and introducing unique genes in model organisms.

Functions of microbial bioremediation

Under this project, the diversity of microbes involved in bioremediation of specific pollutants has been studied and their modes of actions reviewed. However, irrespective of the cellular compounds involved, microbes achieve bioremediation through one or more of the following:

  • Biosorption
  • Complexation
  • Bioassimilation
  • Enzymatic transformation
  • Mineralization

These common pathways guide researchers in designing bioreactors for efficient removal of pollutants.  Also, enzymes and biofilms have consistently shown importance in bioremediation processes, no matter the pollutant type. While enzymes have been argued to be highly efficient in bioremediation, their cost of purification and stability issues have limited researchers in developing practical applications for the molecules.

Clearly, the application of these microbes in a real-time remediation system or bioreactor is far from being possible. On the other hand, researchers have designed, tested and implemented several lab-scale bioreactors (Firmino et al., 2015; Hossain et al., 2015). However, the actual application of such systems on a wide scale is rare. This suggests that there are issues with upscaling and logistics of big operations.

One successful example of applying bioremediation in large-scale cleanup is the Mumbai oil spill of 2010, when ‘oilzapper’; a patented microbial consortium capable of degrading oil was applied to the polluted beach, with successful outcomes (Maharashtra Pollution Control Board, 2010). However, in case of Deepwater Horizon spill, bioremediation operations was not be possible, but policymakers relied on natural bioremediation processes to mitigate the disaster (Atlas & Hazen, 2011).

Emerging trends in bioremediation

Subsequently, the future of bioremediation as a technology depends on understanding the drivers (biotic and abiotic) influencing the natural selection of organisms capable of metabolizing pollutants. Moreover, information on the underlying genomes and proteasomes involved in bioremediation will also contribute towards designing efficient bioremediation systems. On the other hand, analysis of relevant genomic and proteomic sequences, their diversity and also evolutionary relationships existing between them can contribute towards designing efficient bioremediation systems. However, sequence information can help in studying functional variations of different variants of important genes and proteins existing in nature. Such information could further help design more efficient proteins or microbes or whole systems. Also, systems biology information like molecular pathways and interactions existing within the cell and outside (in biofuels for example) can shine the light on the secondary factors influencing the central bioremediation processes.

Instances of microbial bioremediation

Knowledge of these factors will help predict the behaviors of organisms under different conditions of bioremediation, as argued by Jafari, Danesh, & Ghoosta, (2013). However, existing research has determined sequences and structural information of cellular components involved in bioremediation, but extensive research is still lacking in their diversity and modification for higher efficiency products.

Apart from the removal of pollutants, the end-products or by-products are also important in the  remediation system (Jonsson & Haller, 2014; Tripathi, Edrisi, O’Donovan, Gupta, & Abhilash, 2016). Typically researchers look for either less toxic forms of pollutants or complete mineralization of the initial pollutant. However, the next generation bioremediation protocols will focus on synthesizing useful-by products that could be consumed by humans. The figure below shows the major useful by-products that researchers target in designing remediation systems, focusing mainly on energy.

By-products for bioremediation

By-products for bioremediation

For example, research however attempts to efficiently convert the chemical energy stored in wastewater to electricity through the production of electrons during metabolic activities (Jadhav, Ghosh, & Ghangrekar, 2017).

Similarly, research conducted in coupling bioremediation with biofuel production, using bacteria and microalgae helped turn waste into biofuel  (Thomas et al., 2016; Waghmare, Kadam, Saratale, & Govindwar, 2014).

Future scope

Furthermore, research will explore the role of phytoremediation in mediating environmental pollution. Moreover, phytoremediation is advantageous over microbial remediation considering their economic feasibility, widespread pollution degradation capacity, higher public acceptance and also a high rate of contaminant reduction or degradation (Tangahu et al., 2011).

Therefore, bioinformatics and biostatistics analyses conducted on phytoremediation data will help evaluate and justify the need for genetically modified organisms. Henceforth, GMO plants will possess previously identified efficient metabolic processes, enzymes, genes or operons capable of bioremediation specific pollutant. However, genomics, proteomics and metabolomics concerned with bioremediation help to explore in devising possible solutions targeting specific pollutants. Subsequently, the following areas under bioremediation will be explored:

  1. Identification and comparison of gene and protein sequences capable of efficient removal of contaminants.
  2. Diversity and Phylogenetic studies of important gene and protein sequences involved in bioremediation processes.
  3. Application of important genes in plant biotechnology.

GMO plants capable of remediation wide range of waste effluents and polluted lands can be advantageous and also be a potential candidate for practical applications.


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  • Hossain, K., Ismail, N., Rafatullah, M., Quaik, S., Nasir, M., Maruthi, A., & Shaik, R. (2015). Bioremediation of textile effluent with membrane bioreactor using the white-rot fungus Coriolus versicolor. Journal of Pure and Applied Microbiology, 1(9), 1979–87. Retrieved from
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  • Tripathi, V., Edrisi, S. A., O’Donovan, A., Gupta, V. K., & Abhilash, P. C. (2016). Bio-remediation for Fueling the Biobased Economy. Trends in Biotechnology.
  • Waghmare, P. R., Kadam, A. A., Saratale, G. D., & Govindwar, S. P. (2014). Enzymatic hydrolysis and characterization of waste lignocellulosic biomass produced after dye bio-remediation under solid state fermentation. Bioresource Technology, 168(2014), 136–141.
Chandrika Kapagunta

Chandrika Kapagunta

Research Analyst at Project Guru
Chandrika is a nature enthusiast with special love for the marine world. Her Master’s degree in Marine Biotechnology and Scuba Diving experience has made her a strong advocate of environment and marine conservation, especially through bioremediation. She believes in finding solutions of everyday human problems in nature, be it medicines, technology or philosophy. Having worked as a volunteer at The Bombay Natural History Society and as a Senior Research Fellow at Central Institute of Fisheries Education, she has had exposure to the current state of the academic research, specifically in the field of environmental biotechnology.
Chandrika Kapagunta

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