The discussions on allergic disorders till now emphasized on the prevalence and severity, besides highlighting the significant treatment options. Henceforth, it is essential to discuss the economics associated with the different treatment options. This demands the exploration of the cost of illness also known as the burden of disease. Read more »
Paracetamol was discovered by McNeil Laboratories in 1955 as an analgesic and antipyretic for children and is further said to be a non-opiod analgesic and is often known as acetaminophen. It is considered as a first line analgesic and is considered safe and effective in pain relieve against muscoskeletal pain caused due to rheumatoid arthritis and fever. Read more »
Penicillin was discovered by Ernest Duchesne in 1896 and Alexander Fleming by isolating the antibiotic substance from the fungus Penicillium chrysogenum. The fungus produces this antibiotic when its food resources are limited as a mechanism to kill bacteria. It is used in the treatment of a variety of infections (such as scarlet fever, skin, ear and throat infection, pneumonia, rheumatic fever, chorea). Read more »
The prevalence of different allergies has been explored in the previous articles across 5 case countries and comparisons have been drawn with prevalence in India. The findings implicate that incidence of several allergic responses have been rising continuously mainly due to development in technology and increase in severe pollution. Allergic reactions in present times are affecting nearly 20-30% of the Indian population. Allergy has become a cause of concern for both individuals and government. This is because of its social and economic impact in terms of cost of healthcare, loss of working hours and lower quality of life among others. This article explores the social and economic burden of allergic diseases in India.
In the previous article Drug related hypersensitivity, prevalence, diagnosis and therapeutic considerations, we discussed about how different drugs lead to different allergic responses. However, it is important that mechanism of different drug is studied which leads to ADR. In the present article Abacavir, a drug which is used for the treatment and prevention of Human Immuno Deficiency Virus (HIV) (Hewitt et al., 2002) is being discussed. Abacavir is a synthetic carbocyclic nucleoside which is categorised under the class of Nucleoside Reverse Transcriptase Inhibitors. Read more »
Research has shown that drug related hypersensitivity is an immune mediated response towards a drug. However, adverse reaction of the drug varies from person to person. Antibiotics and non steroidal anti inflammatory drugs are the most common causes of hypersensitive reactions. The chances of developing hypersensitive reactions are higher when the patient takes the drug intra dermally. It should nevertheless be noted that drug allergies are not inherited. Both organ specific and systemic symptoms have been observed due to drug-related hypersensitivity. Look out for common symptoms such as: Read more »
Insect sting can cause allergic response which results in pain, itching, redness and swelling. Furthermore, people allergic to stinging venom can cause more serious reaction i.e. anaphylaxis (Bernstein et al., 2011; Department of Health, 2016). Insect Allergy is also known as Hymenoptera Venom Allergy (HVA). This induces large local reaction (LLR) or systemic allergic responses which affect a local area of more than 10cm within 24 hours at the sting site. Hymenoptera belongs to sub-order Aculeate category and includes super-families of Apoidea, Vespidae, and Formicidae (Jutel et al 2013).
Occupational allergy is an allergic reaction caused when exposed to allergenic substance found at work place. This can be both indoor or outdoor. It is an important public health issue due to its high prevalence and socio-economic burden. It contributes significantly to the global burden of Asthma. Similarly among other diseases like; rhinitis, eczema, skin diseases and conjunctivitis can also increase due to this allergy.