Case study
Industrial Overview

Challenges faced by the aviation industry

Challenges faced by the aviation industryAviation is an important parameter of a nation’s economic health. This is a vital industry which contributes significantly to the Gross Domestic Product (GDP) and provides employment to the masses. Which in turn raises their standard of living. Continue »

Trade relationship management (TRM)

Trade relationship management (TRM)There was a time when markets were controlled solely by the demand-supply mechanism. The only humans who could influence the market were the sellers (Panwar, 2001). Things have however changed over time. Continue »

Recently on Knowledge Tank

Expectancy theory and performance management system

Victor Vroom proposed the expectancy theory of motivation in 1965. It is the most comprehensive and realistic, underlying other motivation theories. Expectancy theory featuring the performance management system states that the motivation of employees and their reflected behavior in the workplace depends upon the following key elements:

  • Expectancy,
  • Instrumentality and
  • Valence.

Expectancy is a belief for performing a job satisfactorily, instrumentality involves rewards for performances and valence focuses on the value of the positive rewards (Parijat & Bagga, 2014). Continue »

Role of circulating microRNA in predicting myocardial infarction

Myocardial infarction (MI) is a condition when the heart does not receive enough blood flow due to the narrowing of the blood vessels. It is also known as heart attack and caused by the plaque deposition on the arterial walls. It is a leading cause of deaths worldwide. According to several reports, micro RNA plays a critical role in myocardial infarction (Fichtlscherer et al., 2010). MicroRNA helps in controlling many biological processes and plays a role in health and heart diseases. Depletion of Dicer (a microRNA processing enzyme) leads to various defects in angiogenesis, vessel formation and cardiac development (Van Rooij and Olson, 2007). MicroRNA is detected in blood circulation and therefore can be used as potent biomarkers for cardiovascular disease (Mitchell et al., 2008). These microRNAs are also called circulating microRNA. Continue »

Importance of lipoprotein in detecting cardiovascular diseases

Cardiovascular diseases are caused by a condition known as atherosclerosis. In this, a substance called plaque builds up in the walls of arteries, making them narrow and restricting the blood flow which leads to heart attack or stroke. The plaque formation occurs due to the buildup of cholesterol in the blood vessels. This happens when the low density lipoprotein (LDL) carrying the cholesterol to the cells enters the inner lining of blood vessels and are trapped in the artery walls. Continue »

Technologies and resources used in biomarker discovery and development

Biomarker development has served as an indicator of disease progression and response to therapeutic intervention. The conventional approach involved the study of molecules (considered as biomarker) in regulatory pathways but with the advent of technologies and resources, the development and biomarker discovery gotten easier (Tong & Li, 2016). Continue »

Application of Biomarkers in personalized medicine

The concept of personalized medicine was first promoted with pharmacogenomics data on oncology trials which demonstrated subject’s unique genetic makeup (genome) influence on their response to medications (The Office of the Commissioner FDA, 2015). Treatment biomarkers comprise of genes or a DNA sequence or an RNA strand which expresses uniquely in every individual. Continue »

Analysis to find impact of FDI inflows on GDP of India

Foreign Direct Investment (FDI) is a vital catalyst for economic growth. Over the years, FDI has developed impressively in its significance for Indian economy especially after liberalization. The previous article highlighted the importance of Gross Domestic Product (GDP) as one of the main indicators of economic performance of a country. The aim of this article is to empirically analyse and investigate the impact of FDI inflows on GDP in India after establishing long run association and causality between these two variables. Continue »

Classification and application of different biomarkers

Biomarkers are any substance of biological origin, which is used as an indicator for certain medical conditions. Atkinson et al., (2001) defined the biomarker as:

“A characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention”.

The assessment stated that a factual biomarker definition includes almost any measurement imitating an interaction between a potential hazard (biological, chemical or physical) and a biological system. The response of biomarkers measure functional and cellular level physiological, biochemical or a molecular interaction. Continue »

Factors affecting the economic performance of a country

Economic performance of a country is measured by economic growth and the most commonly used indicator for economic growth of a country, its Gross Domestic Product (GDP) or Gross National Product (GNP). GDP is the aggregate value of all final goods and services produced in the domestic territory of an economy or a country in a certain period of time. GNP is GDP adjusted for domestic workforce working abroad and the foreign workforce working in the domestic economy. Although economic growth alone is not a sufficient condition for economic development, it is a necessary condition for an economy to be healthy and performing well. Continue »

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